Clinical Studies and Other Therapeutic Resources

Here’s your one-stop source for viewing and downloading NOCITA® (bupivacaine liposome injectable suspension) white papers, clinical studies and more.

NOCITA Technical Monograph

Reviews post-operative pain management approaches and provides a therapeutic overview of safety and efficacy of FDA-approved long-acting local anesthetic use in dogs and cats. Comprehensive bibliography included.

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Extended Release Local Anesthetic Use in Veterinary Surgical Patients

Reviews use of local anesthetics in dogs and cats, particularly bupivacaine, and introduces a formulation of prolonged release bupivacaine.

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Clinical Effectiveness Study and Results in Dogs

Randomized, placebo-controlled clinical field study evaluating the effectiveness of bupivacaine liposome injectable suspension for post-surgical analgesia in dogs undergoing stifle surgery.

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Safety Evaluation of EXPAREL® (DepoFoam® Bupivacaine) Administered by Repeated Subcutaneous Injection in Rabbits and Dogs: Species Comparison

A study of repeat-dose toxicity in rabbits and dogs to compare the potential local and systemic toxicities of EXPAREL and bupivacaine HCl (Bsol), and the reversibility of any effects.

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The Safety of Liposome Bupivacaine Following Various Routes of Administration in Animals

Results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs.

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Online Continuing Education Module

Earn one hour Continuing Education (CE) credit with this RACE-approved online course designed for veterinarians and veterinary technicians.

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