Your links to the most up-to-date therapeutic information and support.


Continuing Education

Complete an educational online course designed for Veterinarians and Veterinary Technicians to stay ahead of current trends and up-to-date on cutting-edge techniques.

Clinical References

Here’s your one-stop source for viewing and downloading NOCITA® (bupivacaine liposome injectable suspension) white papers, recent clinical studies and more.

NOCITA Technical Monograph

The NOCITA®(bupivacaine liposome injectable suspension) technical monograph reviews current post-operative pain management approaches as well as the therapeutic overview of safety and efficacy of FDA-approved long-acting local anesthetic.

Comprehensive bibliography included.

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Clinical Effectiveness Study and Results

Pilot, randomized, placebo-controlled clinical field study to evaluate the effectiveness of bupivacaine liposome injectable suspension for the provision of post-surgical analgesia in dogs undergoing stifle surgery published in BMC Veterinary Research. 

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An Extended Release Local Anesthetic: Potential for Future Use in Veterinary Surgical Patients

One of the most effective means of preventing the transduction and transmission of acute and perioperative pain is through the use of local anesthetics. This paper will review the use of local anesthetics, particularly bupivacaine, in dogs and cats, and introduce a formulation of prolonged release bupivacaine that is in development for dogs and cats.

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Safety Evaluation of EXPAREL® (DepoFoam® Bupivacaine) Administered by Repeated Subcutaneous Injection in Rabbits and Dogs: Species Comparison

EXPAREL (bupivacaine extended-release liposome injection) (DepoFoam bupivacaine) is in development for prolonged postsurgical analgesia. Repeat-dose toxicity studies were conducted in rabbits and dogs to compare the potential local and systemic toxicities of EXPAREL and bupivacaine HCl (Bsol), and the reversibility of any effects.

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The Safety of Liposome Bupivacaine Following Various Routes of Administration in Animals

Local and/or regional analgesic techniques are principal components of many multimodal analgesic techniques. This report presents results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs.

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In-Clinic Tools

Introducing NOCITA into your clinic as part of a multimodal approach to post-operative pain control has never been easier with these simple tools.

Pet Owner Information Sheet

Provides a brief overview of NOCITA and why the veterinarian used it for post-operative pain control.

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Surgical Worksheet

A resource that can be downloaded and printed to help guide consistent peri-operative practices.

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DOG INDICATION: For single-dose infiltration into the surgical site to provide local post-operative analgesia for cranial cruciate ligament surgery in dogs.

IMPORTANT SAFETY INFORMATION: NOCITA® (bupivacaine liposome injectable suspension) is for local infiltration injection in dogs only. Do not use in dogs younger than 5 months of age, that are pregnant, lactating or intended for breeding. Do not administer by intravenous or intra‐arterial injection. Adverse reactions in dogs may include discharge from incision, incisional inflammation and vomiting. Avoid concurrent use with bupivacaine HCl, lidocaine or other amide local anesthetics. Please see the full Prescribing Information for more detail.

Experience the Difference

“We began using Nocita on canine patients undergoing cranial cruciate ligament stabilization surgeries and have been very pleased with the results.  The product is intuitive to use and we have observed nothing but positive effects for our patients post-operatively.  Specifically, these patients appear to bear more significant weight immediately post-op than usually expected, require very little rescue analgesia, and are willing to eat early in the recovery period which has allowed easy transition to oral medications.  Nocita has quickly become standard protocol for analgesia on our canine cruciate ligament stabilization procedures.” 

Veterinary Surgeon

Milwaukee WI

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