Dosing and Administration

Moving needle injection technique for dogs

The technique for injecting NOCITA® (bupivacaine liposome injectable suspension) into a surgical site following cranial cruciate ligament surgery in dogs differs slightly from using traditional bupivacaine formulation, because the liposomes themselves do not readily diffuse from where they are deposited.

Therefore, a moving-needle injection technique is used to inject the suspension into all tissue layers of the surgical field. As bupivacaine is gradually released from individual liposomes, it will diffuse locally into the surrounding tissues.

NOCITA Tissue Infiltration Administration Demonstration

*Cranial cruciate ligament

NOCITA administration

Single-dose administration for dogs

NOCITA is a long-acting, local anesthetic that lasts up to 72 hours post-surgery with just one dose.

A dose of 5.3 mg/kg (0.4 mL/kg) can be given by tissue infiltration injection during surgery for post-operative analgesia following cranial cruciate ligament surgery in dogs.

Now Approved For Cats

NOCITA is now FDA-approved for use in cats as a peripheral nerve block to provide regional post-operative analgesia following onychectomy. Please see the full Prescribing Information for more detail.

Single-dose administration for cats

NOCITA is for administration only once prior to surgery. Cats should receive a dose of 5.3 mg/kg per forelimb (0.4 mL/kg per forelimb, for a total dose of 10.6 mg/kg/cat) as a 4-point nerve block prior to onychectomy. Administration prior to surgery may provide up to 72 hours of pain control. Please see the full Prescribing Information for more dosing and administration detail.

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Experience the Difference

“We began using Nocita on canine patients undergoing cranial cruciate ligament stabilization surgeries and have been very pleased with the results.  The product is intuitive to use and we have observed nothing but positive effects for our patients post-operatively.  Specifically, these patients appear to bear more significant weight immediately post-op than usually expected, require very little rescue analgesia, and are willing to eat early in the recovery period which has allowed easy transition to oral medications.  Nocita has quickly become standard protocol for analgesia on our canine cruciate ligament stabilization procedures.” 

Veterinary Surgeon

Milwaukee WI

DOG INDICATION: For single-dose infiltration into the surgical site to provide local post-operative analgesia for cranial cruciate ligament surgery in dogs.

IMPORTANT SAFETY INFORMATION: NOCITA® (bupivacaine liposome injectable suspension) is for local infiltration injection in dogs only. Do not use in dogs younger than 5 months of age, that are pregnant, lactating or intended for breeding. Do not administer by intravenous or intra‐arterial injection. Adverse reactions in dogs may include discharge from incision, incisional inflammation and vomiting. Avoid concurrent use with bupivacaine HCl, lidocaine or other amide local anesthetics. Please see the full Prescribing Information for more detail.

CAT INDICATION: For use as a peripheral nerve block to provide regional post-operative analgesia following onychectomy in cats.

IMPORTANT SAFETY INFORMATION: NOCITA® (bupivacaine liposome injectable suspension) is for use as a peripheral nerve block in cats only. Do not use in cats younger than 5 months of age, that are pregnant, lactating, or intended for breeding. Do not administer by intravenous or intra‐arterial injection. Adverse reactions in cats may include elevated body temperature, infection or chewing/licking at the surgical site. Avoid concurrent use with bupivacaine HCl, lidocaine or other amide local anesthetics. Please see the full Prescribing Information for more detail.

Other therapeutics from Aratana

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Finally, appetite stimulation is in your control.

ENTYCE® (capromorelin oral solution) is the ONLY FDA-approved veterinary therapeutic designed to safely and effectively stimulate appetite in dogs. Administered orally once a day, ENTYCE is appropriate for treating inappetence caused by chronic and acute conditions.

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IMPORTANT SAFETY INFORMATION: ENTYCE® (capromorelin oral solution) is for use in dogs only. Do not use in breeding, pregnant or lactating dogs. Use with caution in dogs with hepatic dysfunction or renal insufficiency. Adverse reactions in dogs may include diarrhea, vomiting, polydipsia, and hypersalivation. Should not be used in dogs that have a hypersensitivity to capromorelin. Please see the full Prescribing Information for more detail.